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Mechanism of Action Comparison# Semaglutide# Semaglutide is a 31-amino acid human GLP-1 analog with three key modifications: an Aib substitution at position 2 for DPP-4 resistance, a C18 fatty diacid at Lys26 for albumin binding, and an Arg substitution at position 34 to prevent mis-acylation
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